Identification of antioxidant activity of two new aromatic ring butyrolactone derivatives from Dictamnus dasycarpus Turcz

The present study carried out a phytochemical investigation on the root barks of Dictamnus dasycarpus Turcz, leading to the isolation and characterization of two new aromatic ring butyrolactone derivatives, dasycarpusphenol acid A (1) and dasycarpusphenol acid B (2). Their structures were elucidated...

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Published in:Chinese journal of natural medicines 2016-11, Vol.14 (11), p.876-880
Main Authors: GUO, Li-Na, PEI, Yue-Hu, XIE, Fei-Xiang, LIU, Lei, CONG, Huan, CUI, Hong-Xia, WANG, Xiao-Li, LI, Wen-Jing, JIAN, Bai-Yu, LIU, Ji-Cheng
Format: Article
Language:English
Subjects:
4-Butyrolactone - chemistry
4-Butyrolactone - isolation & purification
Antioxidant activity
Antioxidants - chemistry
Antioxidants - isolation & purification
Dasycarpusphenol acid A
Dasycarpusphenol acid B
Dictamnus - chemistry
Dictamnus dasycarpus
Molecular Structure
Plant Bark - chemistry
Plant Extracts - chemistry
Plant Extracts - isolation & purification
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Summary:The present study carried out a phytochemical investigation on the root barks of Dictamnus dasycarpus Turcz, leading to the isolation and characterization of two new aromatic ring butyrolactone derivatives, dasycarpusphenol acid A (1) and dasycarpusphenol acid B (2). Their structures were elucidated by using spectroscopic techniques and HR-FAB-MS. Compounds 1 and 2 exhibited antioxidant activity, with their IC50 values being 28.95 and 41.76 mg·mL−1, respectively.
ISSN:1875-5364
1875-5364
DOI:10.1016/S1875-5364(16)30105-4