Interaction between cadmium exposure and infection with the intestinal parasite Moniliformis moniliformis (Acanthocephala) on the stress hormone levels in rats

Parasite infections may influence host's reponse to environmental pollutants. The impact of an infection with the acanthocephalan Moniliformis moniliformis and a simultaneous Cd-exposure on the stress hormone levels of rats was studied. Immediately after the application of cadmium to some rats,...

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Bibliographic Details
Published in:Environmental pollution (1987) 2002-01, Vol.119 (3), p.333-340
Main Authors: Sures, B., Scheef, G., Klar, B., Kloas, W., Taraschewski, H.
Format: Article
Language:English
Subjects:
Acanthocephalans
Animal, plant and microbial ecology
Animals
Applied ecology
Biological and medical sciences
Biomarkers - blood
Cadmium
Cadmium - toxicity
Catecholamines
Chromatography, High Pressure Liquid - methods
Cortisol
Ecotoxicology, biological effects of pollution
Effects of pollution and side effects of pesticides on vertebrates
Environmental Pollutants - toxicity
Epinephrine - blood
Fundamental and applied biological sciences. Psychology
Helminthiasis, Animal - blood
Hydrocortisone - blood
Male
Mammalia
Moniliformis
Moniliformis moniliformis
Nonlinear Dynamics
Norepinephrine - blood
Parasites
Rats
Rats, Wistar
Stress hormones
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Summary:Parasite infections may influence host's reponse to environmental pollutants. The impact of an infection with the acanthocephalan Moniliformis moniliformis and a simultaneous Cd-exposure on the stress hormone levels of rats was studied. Immediately after the application of cadmium to some rats, cortisol levels in all groups of rats, as quantified by radioimmunoassay (RIA), significantly increased. However, infections with M. moniliformis as well as the uptake of Cd reduced significantly the cortisol release compared to untreated controls. While catecholamine concentrations, as determined by high-performance liquid chromatography (HPLC), showed no clear tendency during the experimental period, the ratio of C adrenaline/C noradrenaline in the controls showed the significantly lowest value of all four groups after killing the animals. Thus, the acanthocephalan infection as well as the Cd-exposure and the combination of both treatments affect hormone homeostasis in the rats which probably lead to negative effects on the health of the rat. Therefore parasite infections must be carefully considered in environmental impact studies, as an important factor affecting the host's health.
ISSN:0269-7491
1873-6424
DOI:10.1016/S0269-7491(01)00340-2