Isolation and complete genome characterization of novel reassortant orthoreovirus from common vole (Microtus arvalis)

A novel mammalian orthoreovirus (MRV) strain was isolated from the lung tissue of a common vole ( Microtus arvalis ) with Tula hantavirus infection. Seven segments (L1–L3, M2–M3, S2, and S4) of the Hungarian MRV isolate MORV/47Ma/06 revealed a high similarity with an MRV strain detected in bank vole...

Full description

Saved in:
Bibliographic Details
Published in:Virus genes 2017-04, Vol.53 (2), p.307-311
Main Authors: Fehér, Enikő, Kemenesi, Gábor, Oldal, Miklós, Kurucz, Kornélia, Kugler, Renáta, Farkas, Szilvia L., Marton, Szilvia, Horváth, Győző, Bányai, Krisztián, Jakab, Ferenc
Format: Article
Language:English
Subjects:
Animals
Arvicolinae - genetics
Arvicolinae - virology
Biomedical and Life Sciences
Biomedicine
Hantavirus - genetics
Hantavirus Infections - genetics
Hantavirus Infections - virology
Humans
Medical Microbiology
Molecular Sequence Data
Phylogeny
Plant Sciences
Reassortant Viruses - classification
Reassortant Viruses - genetics
Reassortant Viruses - pathogenicity
Virology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A novel mammalian orthoreovirus (MRV) strain was isolated from the lung tissue of a common vole ( Microtus arvalis ) with Tula hantavirus infection. Seven segments (L1–L3, M2–M3, S2, and S4) of the Hungarian MRV isolate MORV/47Ma/06 revealed a high similarity with an MRV strain detected in bank vole ( Myodes glareolus ) in Germany. The M1 and S3 segment of the Hungarian isolate showed the closest relationship with the sequence of a Slovenian human and a French murine isolate, respectively. The highest nucleotide and amino acid identity values were above 90 and 95% in all of the comparisons to the reference sequences in GenBank, except for the S1 with a maximum of 69.6% nucleotide and 75.4% amino acid identity. As wild rodents are among the main sources of zoonotic infections, the reservoir role of these animals and zoonotic potential of rodent origin MRVs need to be further investigated.
ISSN:0920-8569
1572-994X
DOI:10.1007/s11262-016-1411-1