In vivo reflectance confocal microscopy characterization of silver deposits in localized cutaneous argyria

Summary Localized cutaneous argyria is a rare condition secondary to skin deposition of silver following exposure to substances containing this metal. The clinical appearance and dermoscopy findings require deep melanocytic lesions and particularly melanoma metastasis to be ruled out. Silver deposit...

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Bibliographic Details
Published in:British journal of dermatology (1951) 2016-11, Vol.175 (5), p.1052-1055
Main Authors: García‐Martínez, P., López Aventín, D., Segura, S., Gómez‐Martín, I., Lloreta, J., Ibáñez, J., Elvira, J.J., Pujol, R.M.
Format: Article
Language:English
Subjects:
Aged, 80 and over
Argyria - diagnostic imaging
Dermoscopy - methods
Humans
Male
Microscopy, Confocal - methods
Silver - metabolism
Skin - metabolism
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Summary:Summary Localized cutaneous argyria is a rare condition secondary to skin deposition of silver following exposure to substances containing this metal. The clinical appearance and dermoscopy findings require deep melanocytic lesions and particularly melanoma metastasis to be ruled out. Silver deposits are usually confirmed by scanning electron microscopy and/or energy‐dispersive X‐ray spectroscopy. Herein we describe the in vivo reflectance confocal microscopy (RCM) features observed in one case of localized cutaneous argyria. These features include the presence of a hyperrefractile network in the papillary dermis and a periadnexal dotted bright pattern. In vivo RCM might be a useful tool for an early diagnosis of this uncommon entity. Linked Comment: Youn. Br J Dermatol 2016; 175:870.
ISSN:0007-0963
1365-2133
DOI:10.1111/bjd.14571