Glycated Albumin Identifies Prediabetes Not Detected by Hemoglobin A1c: The Africans in America Study

Following immigration to the US, many Africans transition from a low-normal to a high-normal or overweight body mass index (BMI). This weight change is associated with a high rate of prediabetes in the nonobese. Studies in East Asians reveal that glycated albumin is effective in identifying prediabe...

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Bibliographic Details
Published in:	Clinical chemistry (Baltimore, Md.) Md.), 2016-11, Vol.62 (11), p.1524-1532
Main Authors:	Sumner, Anne E, Duong, Michelle T, Bingham, Brianna A, Aldana, Paola C, Ricks, Madia, Mabundo, Lilian S, Tulloch-Reid, Marshall K, Chung, Stephanie T, Sacks, David B
Format:	Article
Language:	eng
Subjects:	Adult African Americans African Continental Ancestry Group Body Mass Index Cohort Studies Female Glucose Tolerance Test Glycated Hemoglobin A - analysis Humans Male Middle Aged Prediabetic State - blood Prediabetic State - diagnosis Serum Albumin - analysis Young Adult
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Summary:	Following immigration to the US, many Africans transition from a low-normal to a high-normal or overweight body mass index (BMI). This weight change is associated with a high rate of prediabetes in the nonobese. Studies in East Asians reveal that glycated albumin is effective in identifying prediabetes in nonobese Asians. Whether this is true in African immigrants is unknown. Therefore, we evaluated the ability of hemoglobin A (Hb A ) and glycated albumin to detect prediabetes in nonobese (BMI
ISSN:	0009-9147 1530-8561