Transcatheter arterial embolization with ethylene vinyl alcohol copolymer (Onyx) for the treatment of hemorrhage due to uterine arteriovenous malformations

Abstract Purpose The purpose of this study was to evaluate the effectiveness of ethylene vinyl alcohol copolymer ( Onyx) as a single embolic agent for percutaneous arterial treatment of hemorrhage due to uterine arteriovenous malformations (AVMs). Materials and methods Twelve women (mean age, 33 yea...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostic and interventional imaging 2017-05, Vol.98 (5), p.415-421
Main Authors: Barral, P.-A, Saeed-Kilani, M, Tradi, F, Dabadie, A, Izaaryene, J, Soussan, J, Bartoli, J.-M, Vidal, V
Format: Article
Language:English
Subjects:
Adult
Arteriovenous Malformations - complications
Catheterization
Embolization, Therapeutic - methods
Female
Hemorrhage - etiology
Hemorrhage - therapy
Humans
Middle Aged
Polyvinyls - administration & dosage
Radiology
Retrospective Studies
Uterine arteriovenous malformations
Uterine artery embolization
Uterine hemorrhage
Uterus
Uterus - blood supply
Vascular Surgical Procedures
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Purpose The purpose of this study was to evaluate the effectiveness of ethylene vinyl alcohol copolymer ( Onyx) as a single embolic agent for percutaneous arterial treatment of hemorrhage due to uterine arteriovenous malformations (AVMs). Materials and methods Twelve women (mean age, 33 years) with metrorrhagia due to uterine AVMs who were treated by percutaneous arterial embolization using Onyx as a single embolic agent were retrospectively included. The diagnosis of uterine AVM was suggested by pelvic ultrasound and/or magnetic resonance imaging findings and further confirmed by angiography. Clinical files and angiographic examinations were reviewed for angiographic findings, technical and clinical success, procedure complication and further pregnancies. Clinical success was defined by absence of metrorrhagia at 1 month following embolization. Results Sixteen arterial embolization procedures were performed. Angiographically, 6 women had high flow AVM and 6 had low flow AVM. The rate of technical and clinical success was 92% (11/12 patients). One woman with early repeat hemorrhage underwent two embolization procedures and further hysterectomy. No severe complications were observed after embolization. Three women (3/12; 25%) became pregnant following embolization including one full term pregnancy. Conclusion In women with metrorrhagia due to AVM, arterial embolization with Onyx is effective and safe. Additional research is needed to confirm the possibility of future pregnancy after Onyx embolization.
ISSN:2211-5684
2211-5684
DOI:10.1016/j.diii.2016.09.003