The design of wrinkled microcapsules for enhancement of release rate

[Display omitted] Thermally expandable microcapsules (TEMs) with wrinkled shells are prepared by one-step suspension polymerization, allowing for encapsulation and controlled release of cargos. Wrinkling results from concurrent crosslinking of shell copolymers and vaporization of volatile reagents a...

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Bibliographic Details
Published in:Journal of colloid and interface science 2016-09, Vol.478, p.296-302
Main Authors: Ina, Maria, Zhushma, Aleksandr P., Lebedeva, Natalia V., Vatankhah-Varnoosfaderani, Mohammad, Olson, Sean D., Sheiko, Sergei S.
Format: Article
Language:English
Subjects:
Capsules - chemical synthesis
Capsules - chemistry
Cargo
Controlled release
Controlled wrinkleness
Drug delivery systems
Drug Liberation
Encapsulation
Particle Size
Polymerization
Polymers - chemical synthesis
Polymers - chemistry
Reagents
Release rate control
Surface Properties
Surface-to-volume ratio
Vaporization
Wrinkled microcapsule
Wrinkling
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Summary:[Display omitted] Thermally expandable microcapsules (TEMs) with wrinkled shells are prepared by one-step suspension polymerization, allowing for encapsulation and controlled release of cargos. Wrinkling results from concurrent crosslinking of shell copolymers and vaporization of volatile reagents along with density increase upon polymerization. Through control of the vapor pressure of the reagents and systematic variation of the suspension composition, microcapsules with different degrees of wrinkling are prepared, ranging from locally dimpled to highly crumpled morphologies. The corresponding increase of the surface-to-volume ratio results in increasing release rate of encapsulated oil red dye as a model cargo. As such, in addition to shell thickness and radius, the wrinkleness provides an effective control parameter for adjusting the release rate. The wrinkled microcapsules with a large surface-to-volume ratio may find applications in drug delivery, chemicals scavenging, and self-healing materials.
ISSN:0021-9797
1095-7103
DOI:10.1016/j.jcis.2016.06.022