Vertebral Artery Hypoplasia and Posterior Circulation Infarction in Patients with Isolated Vertigo with Stroke Risk Factors

Background We aimed in this study to investigate the prevalence of vertebral artery hypoplasia (VAH) in a population with isolated vertigo in association with stroke risk factors, to determine whether VAH is an independent risk factor for posterior circulation infarction (PCI). Methods We sequential...

Full description

Saved in:
Bibliographic Details
Published in:Journal of stroke and cerebrovascular diseases 2017-02, Vol.26 (2), p.295-300
Main Authors: Zhang, Dao Pei, MD, Lu, Gui Feng, MM, Zhang, Jie Wen, PhD, Zhang, Shu Ling, MM, Ma, Qian Kun, MM, Yin, Suo, MM
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Brain Infarction - diagnostic imaging
Brain Infarction - epidemiology
Brain Infarction - etiology
Cardiovascular
Cerebral Angiography
Diffusion Magnetic Resonance Imaging
Female
Humans
hypoplasia
Logistic Models
Magnetic Resonance Angiography
Male
Middle Aged
Multivariate Analysis
Neurology
Risk Factors
stroke
Stroke - diagnostic imaging
Stroke - epidemiology
Stroke - etiology
vertebral artery
Vertebral Artery - abnormalities
Vertebral Artery - diagnostic imaging
vertebrobasilar insufficiency
Vertigo
Vertigo - complications
Vertigo - diagnostic imaging
Vertigo - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background We aimed in this study to investigate the prevalence of vertebral artery hypoplasia (VAH) in a population with isolated vertigo in association with stroke risk factors, to determine whether VAH is an independent risk factor for posterior circulation infarction (PCI). Methods We sequentially enrolled 245 patients with isolated vertigo with at least 1 vascular risk factor, who were divided into PCI and non-PCI groups, according to present signs of acute infarction on diffusion-weighted magnetic resonance imaging. All patients underwent magnetic resonance angiography and cervical contrast-enhanced magnetic resonance angiography to screen for VAH. Univariate and multivariate logistic regression analyses were performed to identify the significant risk factors for PCI. Results VAH was found in 64 of 245 patients (26%). VAH (odds ratio [OR] = 2.70, 95%confidence interval [CI] 1.17-6.23, P  = .020), median stenosis of the posterior circulation (OR = 7.09, 95%CI = 2.54-19.79, P  
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2016.09.020