Measurement of haemolysis markers following transfusion of uncrossmatched, low‐titre, group O+ whole blood in civilian trauma patients: initial experience at a level 1 trauma centre

SUMMARY Background/Objectives The safety of administering uncrossmatched, group O, cold‐stored, whole blood (cWB) during civilian trauma resuscitation was evaluated. Methods/Materials Male trauma patients with haemorrhage‐induced hypotension who received leuko‐reduced uncrossmatched group O+, low ti...

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Bibliographic Details
Published in:Transfusion medicine (Oxford, England) England), 2017-02, Vol.27 (1), p.30-35
Main Authors: Seheult, J. N., Triulzi, D. J., Alarcon, L. H., Sperry, J. L., Murdock, A., Yazer, M. H.
Format: Article
Language:English
Subjects:
ABO Blood-Group System
Adult
adverse events
Bilirubin - blood
Biomarkers
Blood Transfusion
civilian
Creatinine - blood
Female
haemolysis
Haptoglobins - metabolism
Hemolysis
Humans
L-Lactate Dehydrogenase - blood
Male
Middle Aged
Potassium - blood
resuscitation
transfusion
trauma
Trauma Centers
whole blood
Wounds and Injuries - blood
Wounds and Injuries - therapy
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Summary:SUMMARY Background/Objectives The safety of administering uncrossmatched, group O, cold‐stored, whole blood (cWB) during civilian trauma resuscitation was evaluated. Methods/Materials Male trauma patients with haemorrhage‐induced hypotension who received leuko‐reduced uncrossmatched group O+, low titre (
ISSN:0958-7578
1365-3148
DOI:10.1111/tme.12372