Meat, dairy, and cancer

In 2007 the World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) report judged that the evidence for an association between red and processed meat consumption and colorectal cancer was convincing. In addition, the effect of other animal products on cancer risk has been s...

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Bibliographic Details
Published in:	The American journal of clinical nutrition 2014-07, Vol.100, p.386S-393S
Main Authors:	Abid, Zaynah, Cross, Amanda J, Sinha, Rashmi
Format:	Article
Language:	eng
Subjects:	Animals calcium Calcium, Dietary - adverse effects Cancer clinical nutrition cohort studies colorectal neoplasms Colorectal Neoplasms - etiology Colorectal Neoplasms - prevention & control dairy consumption Dairy products Diet Feeding Behavior heme iron heterocyclic amines Humans Male Meat - adverse effects meat consumption Meat products meta-analysis Milk Nutrition research Oncology polycyclic aromatic hydrocarbons processed meat prostatic neoplasms Prostatic Neoplasms - etiology risk Risk factors urinary bladder neoplasms Urinary Bladder Neoplasms - etiology
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Summary:	In 2007 the World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) report judged that the evidence for an association between red and processed meat consumption and colorectal cancer was convincing. In addition, the effect of other animal products on cancer risk has been studied, and the WCRF/AICR report concluded that milk probably decreases the risk of colorectal cancer but diets high in calcium probably increase the risk of prostate cancer, whereas there was limited evidence for an association between milk and bladder cancer and insufficient evidence for other cancers. There are several potential mechanisms relating meat to cancer, including heterocyclic amines, polycyclic aromatic hydrocarbons, N-nitroso compounds, and heme iron. Although the evidence in favor of a link between red and processed meat and colorectal cancer is convincing, the relations with other cancers are unclear. In this review, we summarize cohort studies conducted by the National Cancer Institute on meat and dairy intake in relation to cancer since the 2007 WCRF/AICR report. We also report the findings of meta-analyses published since 2007.
ISSN:	0002-9165 1938-3207