Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction

We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients. A group of 1,598 patients were enrolled and divided into...

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Bibliographic Details
Published in:Cardiology journal 2016-01, Vol.23 (5), p.505-512
Main Authors: Açıkgöz, Sadık Kadri, Açıkgöz, Eser, Şensoy, Barış, Topal, Salih, Aydoğdu, Sinan
Format: Article
Language:English
Subjects:
Adult
Biomarkers - blood
Cholesterol, HDL - blood
Coronary Angiography
Electrocardiography
Female
Follow-Up Studies
Heart attacks
Hospital Mortality - trends
Humans
Male
Middle Aged
Monocytes - pathology
Mortality
Retrospective Studies
Risk Factors
ST Elevation Myocardial Infarction - blood
ST Elevation Myocardial Infarction - diagnosis
ST Elevation Myocardial Infarction - mortality
Survival Rate - trends
Time Factors
Turkey - epidemiology
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Summary:We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients. A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis. MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308-5.950), in-hospital MACE (HR 1.501, 95% CI 1.015-1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225-4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064-1.552, p = 0.009). MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.
ISSN:1897-5593
1898-018X
1897-5593
DOI:10.5603/CJ.a2016.0026