Serial amnioinfusions for fetal pulmonary palliation in fetuses with renal failure

Fetal lower urinary tract obstruction (LUTO) encompasses a heterogeneous group of congenital pathologies and generally results in oligohydramnios. Fetal intervention (e.g. vesicoamniotic shunting, fetal cystoscopy) has traditionally been reserved for cases with a favorable renal profile, while those...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2017-01, Vol.30 (2), p.174-176
Main Authors: Haeri, Sina, Simon, David H, Pillutla, Kartik
Format: Article
Language:English
Subjects:
Abnormalities, Multiple - prevention & control
Adult
Amniotic Fluid
Female
Fetal Diseases - diagnosis
Fetal Diseases - therapy
Fetal Growth Retardation
Humans
Infant, Newborn
Lung - abnormalities
Lung Diseases - prevention & control
Male
Oligohydramnios - diagnosis
Pregnancy
Renal Insufficiency - complications
Renal Insufficiency - diagnostic imaging
Renal Insufficiency - therapy
Renal Insufficiency - urine
Ultrasonography, Prenatal
Urinary Bladder Neck Obstruction - complications
Urinary Bladder Neck Obstruction - diagnostic imaging
Urinary Bladder Neck Obstruction - therapy
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Summary:Fetal lower urinary tract obstruction (LUTO) encompasses a heterogeneous group of congenital pathologies and generally results in oligohydramnios. Fetal intervention (e.g. vesicoamniotic shunting, fetal cystoscopy) has traditionally been reserved for cases with a favorable renal profile, while those with unfavorable renal function have been offered termination or expectant management with the latter leading to high incidence of marked pulmonary hypoplasia, neonatal morbidity and mortality. Here, we describe two cases, which were not candidates for traditional intervention based on abnormal fetal renal function, who elected to proceed with serial amnioinfusions for fetal pulmonary palliation to attenuate the risk of pulmonary hypoplasia.
ISSN:1476-7058
1476-4954
DOI:10.3109/14767058.2016.1165202