Native Electrocardiographic QRS Duration after Cardiac Resynchronization Therapy: the Impact on Clinical Outcomes and Prognosis

Highlights • Reversal of electrical remodeling (RER) after CRT is determined by narrowing of the intrinsic electrocardiographic QRS duration. • The present study addressed the impact of RER on echocardiographic and prognostic outcomes after CRT. • RER leads to higher rates of functional and volumetr...

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Bibliographic Details
Published in:Journal of cardiac failure 2016-10, Vol.22 (10), p.772-780
Main Authors: Karaca, Oguz, Cakal, Beytullah, Omaygenc, Mehmet Onur, Gunes, Haci Murat, Cakal, Sinem Deniz, MD, Kizilirmak, Filiz, Gokdeniz, Tayyar, Barutcu, Irfan, Boztosun, Bilal, Kilicaslan, Fethi
Format: Article
Language:English
Subjects:
Aged
Analysis of Variance
Cardiac Resynchronization Therapy - methods
Cardiac Resynchronization Therapy - mortality
cardiac resynchronization therapy response
Cardiovascular
Cause of Death
Cohort Studies
Electrocardiography - methods
Female
Heart Failure, Systolic - diagnostic imaging
Heart Failure, Systolic - mortality
Heart Failure, Systolic - therapy
Humans
Kaplan-Meier Estimate
Logistic Models
Male
Middle Aged
mitral regurgitation
Mitral Valve Insufficiency - diagnostic imaging
Mitral Valve Insufficiency - mortality
Mitral Valve Insufficiency - therapy
Multivariate Analysis
Native QRS duration
Prognosis
Retrospective Studies
reversed electrical remodeling
Risk Assessment
Severity of Illness Index
Survival Rate
Treatment Outcome
Ventricular Remodeling - physiology
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Description
Summary:Highlights • Reversal of electrical remodeling (RER) after CRT is determined by narrowing of the intrinsic electrocardiographic QRS duration. • The present study addressed the impact of RER on echocardiographic and prognostic outcomes after CRT. • RER leads to higher rates of functional and volumetric CRT response. • Native QRS narrowing relates to improvement in both MR severity and mitral geometry. • Patients with RER derive more benefit from CRT in terms of death and hospitalization.
ISSN:1071-9164
1532-8414
DOI:10.1016/j.cardfail.2016.04.001