Electrochemical Polymerization of PEDOT/Biomolecule Composite Films on Microelectrodes for the Measurement of Extracellular Field Potential

Microelectrode arrays (MEAs) are very powerful sensor devices for the non-invasive measurement of extracellular field potentials from excited cells. In this study, new types of interfaces were developed on MEAs by exploiting the electrochemical polymerization of conducting polymers with biomolecules...

Full description

Saved in:
Bibliographic Details
Published in:Denki kagaku oyobi kōgyō butsuri kagaku 2016/05/05, Vol.84(5), pp.354-357
Main Authors: SUZUKI, Masato, NAKAYAMA, Masamune, TSUJI, Kiyotaka, ADACHI, Taiji, SHIMONO, Ken
Format: Article
Language:eng ; jpn
Subjects:
Biomolecules
Cardiomyocyte
Conducting polymers
Devices
Electrochemical Polymerization
Electrodes
Microelectrodes
Multielectrode Array
PEDOT
Polymerization
Polysaccharides
Sensor arrays
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Microelectrode arrays (MEAs) are very powerful sensor devices for the non-invasive measurement of extracellular field potentials from excited cells. In this study, new types of interfaces were developed on MEAs by exploiting the electrochemical polymerization of conducting polymers with biomolecules. The composite films were composed of poly(3,4-ethylenedioxythiophen) (PEDOT) and anionic polysaccharide (gellan gum). The PEDOT/biomolecule composite films had no cytotoxic effect, and reduced the electrode impedance at 1 kHz to 8.84 ± 0.50 kΩ. This biointerface enabled us to record extracellular field potentials derived from the spontaneous beating of cardiomyocytes.
ISSN:1344-3542
2186-2451
DOI:10.5796/electrochemistry.84.354