Safety and Outcomes of Capsule Endoscopy in Patients with Left Ventricular Assist Device: a Single-Center Retrospective Case Series

Obscure gastrointestinal bleeding (GIB) in patients with continuous-flow left ventricular assist devices (CF-LVAD) is common. Capsule endoscopy (CE) can be used in the diagnosis of obscure GIB. Safety and outcomes of CE in patients with CF-LVAD are unknown. The aim is to define the safety and outcom...

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Bibliographic Details
Published in:Journal of cardiovascular translational research 2016-08, Vol.9 (4), p.402-404
Main Authors: Hanson, Brian J., Koene, Ryan J., Roy, Samit S., Eckman, Peter M., John, Ranjit, Chaudhary, Nadeem A., Vega-Peralta, Jose
Format: Article
Language:English
Subjects:
Aged
Arteriovenous Malformations - complications
Biomedical Engineering and Bioengineering
Biomedicine
Capsule Endoscopy - adverse effects
Cardiology
Correspondence
Female
Gastrointestinal Hemorrhage - diagnosis
Gastrointestinal Hemorrhage - etiology
Heart-Assist Devices - adverse effects
Human Genetics
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Minnesota
Predictive Value of Tests
Prosthesis Design
Recurrence
Retrospective Studies
Risk Factors
Ventricular Function, Left
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Summary:Obscure gastrointestinal bleeding (GIB) in patients with continuous-flow left ventricular assist devices (CF-LVAD) is common. Capsule endoscopy (CE) can be used in the diagnosis of obscure GIB. Safety and outcomes of CE in patients with CF-LVAD are unknown. The aim is to define the safety and outcomes of CE in this population. Paitents with CF-LVAD undergoing CE at a single center between 2007 and 2014 were retrospectively reviewed. Thirty-four CE studies were performed. Positive CE occurred in 19 studies. No clinically significant cardiac events occurred. Medical intervention was the most common management strategy. Rebleeding after CE occurred in 10 patients. Patients with active bleeding or lesions such as arteriovenous malformations (AVM) incurred a higher risk of rebleeding, transfusion, and repeated endoscopy. CE is safe in patients with CF-LVAD. The risk of rebleeding was more common in patients with active bleeding or AVM lesions although this result did not reach statistical significance.
ISSN:1937-5387
1937-5395
DOI:10.1007/s12265-016-9701-5