Standardization of Fractional Flow Reserve Measurements

Abstract Pressure wire–based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardize...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2016-08, Vol.68 (7), p.742-753
Main Authors: Toth, Gabor G., MD, Johnson, Nils P., MD, Jeremias, Allen, MD, MSc, Pellicano, Mariano, MD, Vranckx, Pascal, MD, PhD, Fearon, William F., MD, Barbato, Emanuele, MD, PhD, Kern, Morton J., MD, Pijls, Nico H.J., MD, PhD, De Bruyne, Bernard, MD, PhD
Format: Article
Language:English
Subjects:
Accuracy
Acute coronary syndromes
Automation
Blood Flow Velocity - physiology
Cardiology
Cardiovascular
Cardiovascular disease
Catheters
Clinical outcomes
Clinical trials
coronary artery disease
Coronary Artery Disease - diagnosis
Coronary Artery Disease - physiopathology
Coronary Artery Disease - surgery
Coronary vessels
Coronary Vessels - physiology
Data analysis
Decision making
Fractional Flow Reserve, Myocardial - physiology
functional assessment
Heart attacks
Heart failure
Humans
Internal Medicine
Ischemia
Laboratories
Patients
Percutaneous Coronary Intervention
Physiology
Reference Standards
Standardization
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Summary:Abstract Pressure wire–based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardized as possible to avoid technical or operator-related artifacts in pressure recordings. This document proposes a standardized way of acquiring, recording, interpreting, and archiving the pressure tracings for daily practice and for the purpose of clinical research involving a core laboratory. Proposed standardized steps enhance the uniformity of clinical practices and data interpretation.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.05.067