Of Mice and Snakes: A Tail of Oct4

The vertebrate axial skeleton comprises regions of specialized vertebrae, which vary in length between lineages. Aires et al. (2016) uncover a key role for Oct4 in determining trunk length in mice. Additionally, a heterochronic shift in Oct4 expression may underlie the extreme elongation of the trun...

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Bibliographic Details
Published in:Developmental cell 2016-08, Vol.38 (3), p.224-226
Main Authors: Shylo, Natalia A., Weatherbee, Scott D.
Format: Article
Language:English
Subjects:
Animals
Biological Evolution
Bone and Bones - metabolism
Mice - anatomy & histology
Mice - metabolism
Octamer Transcription Factors - metabolism
Snakes - anatomy & histology
Snakes - metabolism
Torso - anatomy & histology
Citations: Items that this one cites
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Summary:The vertebrate axial skeleton comprises regions of specialized vertebrae, which vary in length between lineages. Aires et al. (2016) uncover a key role for Oct4 in determining trunk length in mice. Additionally, a heterochronic shift in Oct4 expression may underlie the extreme elongation of the trunk in snakes. The vertebrate axial skeleton comprises regions of specialized vertebrae, which vary in length between lineages. Aires et al. (2016) uncover a key role for Oct4 in determining trunk length in mice. Additionally, a heterochronic shift in Oct4 expression may underlie the extreme elongation of the trunk in snakes.
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2016.07.020