The Dilemma of Breast Cancer Treatment and Existing Collagen Vascular Disease: A Case of Scleroderma and Review of the Literature

Collagen vascular diseases present a treatment dilemma for patients with breast cancer. Due to the potential for severe, acute, and late complications of radiation therapy, a history of collagen vascular disease (CVD) is a relative contraindication to breast‐conserving treatment. We present a case o...

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Bibliographic Details
Published in:The breast journal 2016-07, Vol.22 (4), p.451-455
Main Authors: Zaremba, Nicole M., Tamkus, Deimante, DiCarlo, Luciano, Herman, James, Martin, Mersadies, Bumpers, Harvey L.
Format: Article
Language:English
Subjects:
breast cancer
collagen vascular disease
radiation therapy
scleroderma
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Summary:Collagen vascular diseases present a treatment dilemma for patients with breast cancer. Due to the potential for severe, acute, and late complications of radiation therapy, a history of collagen vascular disease (CVD) is a relative contraindication to breast‐conserving treatment. We present a case of early stage breast cancer in a patient with severe scleroderma treated with breast‐conserving surgery without radiation and a brief review of the published literature regarding the therapeutic approach to the patient with CVD and breast cancer.
ISSN:1075-122X
1524-4741
DOI:10.1111/tbj.12600