Microneurosurgery and subsequent gamma knife radiosurgery for functioning pituitary macroadenomas or giant adenomas: one institution’s experience

Highlights • Treatment of functioning pituitary macroadenoma and giant adenoma is challenging. • Combined microneurosurgery and radiosurgery was used in 59 patients. • A promising tumor control rate was achieved and complication rates were reasonably low. • Reduced tumor volume by surgery may be the...

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Bibliographic Details
Published in:Clinical neurology and neurosurgery 2016-06, Vol.145, p.8-13
Main Authors: Fu, Peng, He, Yun-song, Cen, Yong-cun, Huang, Qin, Guo, Ke-tai, Zhao, Hong-yang, Xiang, Wei
Format: Article
Language:English
Subjects:
Adenohypophyseal cells
Adenoma - radiotherapy
Adenoma - surgery
Adolescent
Adult
Age
Aged
Confidence intervals
Conflicts of interest
Female
Follow-Up Studies
Gender
Headaches
Hormonal data
Hospitals
Humans
Male
Microneurosurgery
Microsurgery - adverse effects
Microsurgery - methods
Middle Aged
Multivariate analysis
Neurology
Neurosurgery
Neurosurgical Procedures - adverse effects
Neurosurgical Procedures - methods
NMR
Nuclear magnetic resonance
Optic nerve
Pituitary adenomas
Pituitary Neoplasms - radiotherapy
Pituitary Neoplasms - surgery
Radiation therapy
Radiosurgery - adverse effects
Radiosurgery - methods
Treatment Outcome
Tumors
Young Adult
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Summary:Highlights • Treatment of functioning pituitary macroadenoma and giant adenoma is challenging. • Combined microneurosurgery and radiosurgery was used in 59 patients. • A promising tumor control rate was achieved and complication rates were reasonably low. • Reduced tumor volume by surgery may be the predominant factor in treatment success
ISSN:0303-8467
1872-6968
DOI:10.1016/j.clineuro.2016.03.021