Relationship between abdominal aortic and coronary artery calcification as detected by computed tomography in chronic kidney disease patients

The purpose of this study was to investigate the relationship between abdominal aortic calcification (AAC) and coronary artery calcification (CAC) in chronic kidney disease (CKD) patients. We evaluated 126 asymptomatic CKD patients (mean estimated glomerular filtration rate: 36.1 ± 14.1 mL/min/1.73 ...

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Published in:Heart and vessels 2016-07, Vol.31 (7), p.1030-1037
Main Authors: Takayama, Yohei, Yasuda, Yoshinari, Suzuki, Susumu, Shibata, Yohei, Tatami, Yosuke, Shibata, Kanako, Niwa, Misao, Sawai, Akihiro, Morimoto, Ryota, Kato, Sawako, Ishii, Hideki, Maruyama, Shoichi, Murohara, Toyoaki
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Aorta, Abdominal - diagnostic imaging
Aortic Diseases - diagnostic imaging
Aortic Diseases - epidemiology
Aortography - methods
Area Under Curve
Asymptomatic Diseases
Atherosclerosis
Biomedical Engineering and Bioengineering
Cardiac Surgery
Cardiology
Chi-Square Distribution
Computed Tomography Angiography
Coronary Angiography - methods
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - epidemiology
Coronary vessels
Coronary Vessels - diagnostic imaging
Female
Glomerular Filtration Rate
Humans
Japan - epidemiology
Kidney - physiopathology
Kidney diseases
Logistic Models
Male
Medicine
Medicine & Public Health
Middle Aged
Multidetector Computed Tomography
Multivariate Analysis
Odds Ratio
Original Article
Predictive Value of Tests
Prevalence
Renal Insufficiency, Chronic - diagnosis
Renal Insufficiency, Chronic - epidemiology
Renal Insufficiency, Chronic - physiopathology
Reproducibility of Results
Risk Factors
ROC Curve
Severity of Illness Index
Tomography
Vascular Calcification - diagnostic imaging
Vascular Calcification - epidemiology
Vascular Surgery
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Summary:The purpose of this study was to investigate the relationship between abdominal aortic calcification (AAC) and coronary artery calcification (CAC) in chronic kidney disease (CKD) patients. We evaluated 126 asymptomatic CKD patients (mean estimated glomerular filtration rate: 36.1 ± 14.1 mL/min/1.73 m 2 , mean age 70.3 ± 10.1 years). A non-contrast computed tomography scan was used to determine the abdominal aortic calcification index (ACI) and CAC score, and this relationship was investigated. Among the subjects, AAC was present in 109 patients (86.5 %) as defined by ACI >0 and median ACI was 11.7 %. ACI increased in accordance with advances in CAC score grades (3.0, 5.2, 17.2, and 32.8 % for CAC score 0, 1–100, 101–400, and 401 or more, respectively, p  400 [odds ratio 1.08, 95 % confidence interval (CI) 1.04–1.12, p  
ISSN:0910-8327
1615-2573
DOI:10.1007/s00380-015-0712-y