QCM-DNA biosensor based on plasma modified PT/TiO sub(2) nanocomposites

A quartz crystal microbalance DNA biosensor based on plasma prepared polythiophene /titanium dioxide (PT/TiO sub(2)) nanocomposite was developed for the detection of genetically modified organisms (GMOs). DNA hybridization was studied by quartz crystal microbalance (QCM) and cyclic voltammetry (CV)...

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Bibliographic Details
Published in:Journal of macromolecular science. Part A, Pure and applied chemistry Pure and applied chemistry, 2016-05, Vol.53 (5), p.311-316
Main Authors: Maslakci, Neslihan Nohut, Danas, Fatma Deligoz, Oksuz, Aysegul Uygun
Format: Article
Language:English
Subjects:
Biosensors
Deoxyribonucleic acid
Genetic modification
Microbalances
Nanocomposites
Organisms
Quartz crystals
Titanium dioxide
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Summary:A quartz crystal microbalance DNA biosensor based on plasma prepared polythiophene /titanium dioxide (PT/TiO sub(2)) nanocomposite was developed for the detection of genetically modified organisms (GMOs). DNA hybridization was studied by quartz crystal microbalance (QCM) and cyclic voltammetry (CV) measurements. Single stranded DNA probes were immobilized on the PT/TiO sub(2) coated quartz crystal electrode and the hybridization between the immobilized probe and the target complementary sequence in solution was monitored. The developed QCM-DNA biosensor represented promising results for a real-time, label-free, direct detection of DNA samples for the screening of genetically modified organisms.
ISSN:1060-1325
1520-5738
DOI:10.1080/10601325.2016.1151651