COPART Risk Score, Endothelial Dysfunction, and Arterial Hypertension are Independent Risk Factors for Mortality in Claudicants

Objective The COPART risk score consists of six variables to assess the prognosis of PAOD patients. The flow mediated dilation (FMD) quantifies endothelial function. The aim of this study was to evaluate the mortality prediction of these two variables in a long-term observation of claudicants. Metho...

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Bibliographic Details
Published in:European journal of vascular and endovascular surgery 2016-08, Vol.52 (2), p.211-217
Main Authors: Hackl, G, Jud, P, Avian, A, Gary, T, Deutschmann, H, Seinost, G, Brodmann, M, Hafner, F
Format: Article
Language:English
Subjects:
Aged
Arterial hypertension
Arterial Occlusive Diseases - complications
Arterial Occlusive Diseases - diagnosis
Arterial Occlusive Diseases - mortality
Arterial Occlusive Diseases - physiopathology
Blood Flow Velocity - physiology
COPART risk score
Endothelium, Vascular - physiopathology
Female
Flow mediated dilation
Humans
Hypertension - complications
Hypertension - diagnosis
Hypertension - mortality
Hypertension - physiopathology
Male
Middle Aged
Mortality
PAOD
Peripheral Arterial Disease - complications
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - mortality
Peripheral Arterial Disease - physiopathology
Prognosis
Prospective Studies
Risk Factors
Severity of Illness Index
Surgery
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Summary:Objective The COPART risk score consists of six variables to assess the prognosis of PAOD patients. The flow mediated dilation (FMD) quantifies endothelial function. The aim of this study was to evaluate the mortality prediction of these two variables in a long-term observation of claudicants. Methods 184 consecutive claudicants were included in a prospective observational study over a median observation period of 7.9 (IQR 7.2–8.7) years. The endothelial function was assessed on the day of study inclusion using brachial FMD. Results Three groups were assigned according to the COPART risk score: low risk (LR), n  = 72 (39%); medium risk (MR), n  = 59 (32%); and high risk (HR), n  = 53 (29%). Overall survival rates differed among COPART risk score groups ( p  
ISSN:1078-5884
1532-2165
DOI:10.1016/j.ejvs.2016.05.011