Home dim light melatonin onsets with measures of compliance in delayed sleep phase disorder

Summary The dim light melatonin onset (DLMO) assists with the diagnosis and treatment of circadian rhythm sleep disorders. Home DLMOs are attractive for cost savings and convenience, but can be confounded by home lighting and sample timing errors. We developed a home saliva collection kit with objec...

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Bibliographic Details
Published in:Journal of sleep research 2016-06, Vol.25 (3), p.314-317
Main Authors: Burgess, Helen J., Park, Margaret, Wyatt, James K., Fogg, Louis F.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Circadian Rhythm - radiation effects
diagnosis
Female
field
Housing
Humans
Light
Lighting - adverse effects
Melatonin - metabolism
Middle Aged
Saliva - metabolism
Saliva - radiation effects
Sleep Disorders, Circadian Rhythm - diagnosis
Sleep Disorders, Circadian Rhythm - physiopathology
Time Factors
treatment
Young Adult
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Summary:Summary The dim light melatonin onset (DLMO) assists with the diagnosis and treatment of circadian rhythm sleep disorders. Home DLMOs are attractive for cost savings and convenience, but can be confounded by home lighting and sample timing errors. We developed a home saliva collection kit with objective measures of light exposure and sample timing. We report on our first test of the kit in a clinical population. Thirty‐two participants with delayed sleep phase disorder (DSPD; 17 women, aged 18–52 years) participated in two back‐to‐back home and laboratory phase assessments. Most participants (66%) received at least one 30‐s epoch of light >50 lux during the home phase assessments, but for only 1.5% of the time. Most participants (56%) collected every saliva sample within 5 min of the scheduled time. Eighty‐three per cent of home DLMOs were not affected by light or sampling errors. The home DLMOs occurred, on average, 10.2 min before the laboratory DLMOs, and were correlated highly with the laboratory DLMOs (r = 0.93, P 
ISSN:0962-1105
1365-2869
DOI:10.1111/jsr.12384