Obstetric outcomes in pregnancies with normal nuchal translucency and abnormal ductus venosus Doppler in the first trimester ultrasonography

In the present case-control study, we evaluated obstetric outcomes of pregnancies with normal nuchal translucency (NT) and abnormal ductus venosus (DV) Doppler findings in the first trimester combined screening test for chromosomal abnormalities. All study patients underwent DV Doppler examination,...

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Bibliographic Details
Published in:Journal of obstetrics and gynaecology 2016-05, Vol.36 (4), p.440-443
Main Authors: Seckin, K. D., Karslı, M. F., Baser, E., Yeral, M. I., Tasin, C., Ozgu Erdinc, A. S., Danisman, N.
Format: Article
Language:English
Subjects:
Adult
Birth weight
Case-Control Studies
Chromosome Disorders - diagnostic imaging
Chromosome Disorders - embryology
Clinical outcomes
ductus venosus Doppler
Female
Fetal Heart - abnormalities
Fetal Heart - diagnostic imaging
Gestational Age
Heart Defects, Congenital - diagnostic imaging
Heart Defects, Congenital - embryology
Humans
Infant, Low Birth Weight
Infant, Newborn
Medical screening
nuchal translucency
Nuchal Translucency Measurement - statistics & numerical data
obstetric outcome
Obstetrics
Pregnancy
Pregnancy complications
Pregnancy Complications - diagnostic imaging
Pregnancy Complications - etiology
Pregnancy Outcome
Pregnancy Trimester, First
Premature Birth - etiology
Ultrasonic imaging
Ultrasonography, Doppler
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Summary:In the present case-control study, we evaluated obstetric outcomes of pregnancies with normal nuchal translucency (NT) and abnormal ductus venosus (DV) Doppler findings in the first trimester combined screening test for chromosomal abnormalities. All study patients underwent DV Doppler examination, concurrent with the combined screening test. DV Doppler revealed pathologic findings in 14 pregnant women despite normal NT after the elimination of lost to follow-up and foetal anomaly. Obstetric outcomes of the case patients were compared with a control group that were matched for mean gestational age, and Crown-rump length with normal NT and DV Doppler measurements was selected comprising 88 pregnant women. Regarding maternal outcomes, women with abnormal DV Doppler findings had a higher rate of placental abruption, delivered at an earlier mean gestational age (preterm delivery). Interestingly, a higher rate of spontaneous vaginal delivery rate was observed in these patients. From the foetal perspective, pregnancies with abnormal DV Doppler had lower birth weight and received lower Apgar scores. In conclusion, an abnormal DV Doppler test in the first trimester was associated with poor maternal and foetal obstetric outcomes. These findings should be elucidated in future studies.
ISSN:0144-3615
1364-6893
DOI:10.3109/01443615.2015.1060210