Oral Chinese herbal medicine for kidney nourishment in Alzheimer's disease: A systematic review of the effect on MMSE index measures and safety

Highlights • The effectiveness and safety of oral administration of CHMK cannot be currently determined because of publication bias and the low quality level of the included trials. • Further studies on a larger scale and with more rigorous designs are required to define the role of CHMK in the trea...

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Bibliographic Details
Published in:Complementary therapies in medicine 2015-04, Vol.23 (2), p.283-297
Main Authors: Zeng, Ling-feng, Wang, Ning-sheng, Wang, Qi, Zou, Yuan-ping, Liang, Zhao-hui, Kong, Ling-shuo, Wu, Hai-tao, Liao, Nan-ying, Liang, Xiao-wen, Mo, You-sheng
Format: Article
Language:English
Subjects:
Administration, Oral
Alzheimer Disease - drug therapy
Alzheimer's disease
Alzheimer's disease (AD)
Bias
Chinese herbal medicine (CHM)
Chinese medicine
Drugs, Chinese Herbal - administration & dosage
Drugs, Chinese Herbal - adverse effects
Herbal medicine
Humans
Internal Medicine
Kidney-nourishing
Kidneys
Medical Education
Meta-analysis
Pharmacotherapy
Randomized controlled trial (RCT)
Senile dementia
Systematic review
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Summary:Highlights • The effectiveness and safety of oral administration of CHMK cannot be currently determined because of publication bias and the low quality level of the included trials. • Further studies on a larger scale and with more rigorous designs are required to define the role of CHMK in the treatment of AD.
ISSN:0965-2299
1873-6963
DOI:10.1016/j.ctim.2015.01.014