(68) Ga-PSMA has a high detection rate of prostate cancer recurrence outside the prostatic fossa in patients being considered for salvage radiation treatment

To examine the detection rates of (68) Ga-PSMA-positron emission tomography (PET)/computed tomography (CT) in patients with biochemical recurrence (BCR) after radical prostatectomy (RP), and also the impact on their management. A total of 300 consecutive patients with prostate cancer (PCa) who under...

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Bibliographic Details
Published in:BJU international 2016-05, Vol.117 (5), p.732-739
Main Authors: van Leeuwen, Pim J, Stricker, Phillip, Hruby, George, Kneebone, Andrew, Ting, Francis, Thompson, Ben, Nguyen, Quoc, Ho, Bao, Emmett, Louise
Format: Article
Language:English
Subjects:
Aged
Gallium Radioisotopes
Humans
Male
Middle Aged
Neoplasm Recurrence, Local - diagnostic imaging
Neoplasm Recurrence, Local - radiotherapy
Neoplasm Staging
Positron-Emission Tomography
Prostate-Specific Antigen - blood
Prostatectomy
Prostatic Neoplasms - diagnostic imaging
Prostatic Neoplasms - radiotherapy
Prostatic Neoplasms - surgery
Risk Factors
Salvage Therapy - methods
Tomography, Emission-Computed
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Summary:To examine the detection rates of (68) Ga-PSMA-positron emission tomography (PET)/computed tomography (CT) in patients with biochemical recurrence (BCR) after radical prostatectomy (RP), and also the impact on their management. A total of 300 consecutive patients with prostate cancer (PCa) who underwent (68) Ga-PSMA-PET/CT between February and July 2015 were prospectively included in the Prostate Cancer Imaging (ProCan-I) database. For the present analysis, we included patients with BCR (prostate-specific antigen [PSA] level ≥0.05 and
ISSN:1464-410X
DOI:10.1111/bju.13397