Yttrium-90 microsphere radioembolotherapy in a patient with spontaneously ruptured hepatocellular carcinoma

Abstract Spontaneous rupture of hepatocellular carcinoma (HCC) is a potentially fatal presentation of the disease. Although many options for treatment exist, Yttrium-90 transcatheter arterial radioembolization has not previously been reported. We report a case of a 92-year-old woman found to have a...

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Bibliographic Details
Published in:Clinical imaging 2016-01, Vol.40 (1), p.167-169
Main Authors: Winokur, Ronald S, Talenfeld, Adam D, Mozley, P. David, Madoff, David C
Format: Article
Language:English
Subjects:
Age
Aged, 80 and over
Carcinoma, Hepatocellular - therapy
Embolization, Therapeutic - methods
Fatal
Female
Hepatocellular carcinoma
Humans
Imaging
Liver cancer
Liver Neoplasms - therapy
Localization
Medical diagnosis
Medical imaging
Medical prognosis
Medical services
Microsphere
Microspheres
Mortality
Patients
Radioembolotherapy
Radiology
Rupture
Rupture, Spontaneous
Spontaneous
Surveillance
Treatment Outcome
Tumor rupture
Tumors
Yttrium Radioisotopes - therapeutic use
Yttrium-90
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Summary:Abstract Spontaneous rupture of hepatocellular carcinoma (HCC) is a potentially fatal presentation of the disease. Although many options for treatment exist, Yttrium-90 transcatheter arterial radioembolization has not previously been reported. We report a case of a 92-year-old woman found to have a ruptured HCC treated with radioembolization that showed no viable tumor and no extrahepatic disease at 2 years. While further studies are warranted, this patient’s clinical course may suggest that radioembolization may be an additional palliative treatment option in these patients.
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2015.08.011