Long‐term clinical outcomes after fatty liver screening in patients undergoing coronary angiogram: A prospective cohort study

There is ongoing debate on whether screening for nonalcoholic fatty liver disease (NAFLD) is worthwhile in high‐risk groups. Because of shared risk factors, NAFLD is highly prevalent in patients with coronary artery disease. We aimed to test the hypothesis that NAFLD screening in patients requiring...

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Bibliographic Details
Published in:Hepatology (Baltimore, Md.) Md.), 2016-03, Vol.63 (3), p.754-763
Main Authors: Wong, Vincent Wai‐Sun, Wong, Grace Lai‐Hung, Yeung, Judy Ching‐Lam, Fung, Chloe Yuk‐Kiu, Chan, Jasmine Ka‐Lei, Chang, Zoe Hoi‐Yi, Kwan, Chelsia Tsz‐Yan, Lam, Hiu‐Wan, Limquiaco, Jenny, Chim, Angel Mei‐Ling, Yu, Cheuk‐Man, Chan, Henry Lik‐Yuen
Format: Article
Language:English
Subjects:
Aged
Cardiovascular disease
Cardiovascular diseases
Clinical outcomes
Cohort analysis
Coronary Angiography
Coronary artery
Coronary Stenosis - complications
Coronary Stenosis - mortality
Coronary vessels
Diabetes mellitus
Fatty liver
Female
Health risk assessment
Heart diseases
Hepatology
Hong Kong - epidemiology
Humans
Liver cancer
Liver diseases
Male
Mass Screening
Middle Aged
Myocardial infarction
Non-alcoholic Fatty Liver Disease - complications
Non-alcoholic Fatty Liver Disease - diagnostic imaging
Non-alcoholic Fatty Liver Disease - mortality
Patients
Prospective Studies
Risk factors
Risk groups
Sex ratio
Stenosis
Ultrasonography
Ultrasound
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Summary:There is ongoing debate on whether screening for nonalcoholic fatty liver disease (NAFLD) is worthwhile in high‐risk groups. Because of shared risk factors, NAFLD is highly prevalent in patients with coronary artery disease. We aimed to test the hypothesis that NAFLD screening in patients requiring coronary angiogram would identify high‐risk patients and predict long‐term clinical outcomes. This was a prospective cohort study. NAFLD screening was performed by abdominal ultrasonography before coronary angiogram in 612 consecutive patients. At baseline, 356 (58.2%) patients had NAFLD. NAFLD patients, compared with those without, were more likely to have >50% stenosis in one or more coronary arteries (84.6% vs. 64.1%; P 
ISSN:0270-9139
1527-3350
DOI:10.1002/hep.28253