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Metabolic syndrome in Greek women with polycystic ovary syndrome: prevalence, characteristics and associations with body mass index. A prospective controlled study

Purpose The aim of this study was to estimate the prevalence, to evaluate the characteristics of the metabolic syndrome (MetS) in Greek women with polycystic ovary syndrome (PCOS) and to investigate the correlation of MetS with body mass index (BMI). Methods In a prospective controlled study, 230 Gr...

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Published in:Archives of gynecology and obstetrics 2016-04, Vol.293 (4), p.915-923
Main Authors: Kyrkou, Giannoula, Trakakis, Eftichios, Attilakos, Achilleas, Panagopoulos, Periklis, Chrelias, Charalampos, Papadimitriou, Anastasios, Vaggopoulos, Vasilis, Alexiou, Eleni, Mastorakos, Georgios, Lykeridou, Aikaterini, Kassanos, Dimitrios, Papaevangelou, Vasiliki, Papantoniou, Nikolaos
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Language:English
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Summary:Purpose The aim of this study was to estimate the prevalence, to evaluate the characteristics of the metabolic syndrome (MetS) in Greek women with polycystic ovary syndrome (PCOS) and to investigate the correlation of MetS with body mass index (BMI). Methods In a prospective controlled study, 230 Greek female patients with PCOS and 155 age-matched healthy controls were enrolled. Diagnosis of PCOS was based on the revised criteria of Rotterdam. Both groups were examined for MetS. Diagnosis of MetS was based on the revised criteria of International Diabetes Federation (IDF). Results The prevalence of the MetS was 12.6 %, nearly sevenfold higher than the controls. Elevated fasting plasma glucose (7.0 vs. 1.9 %) and elevated triglycerides (10.4 vs. 3.2 %) were more frequent in the PCOS cohort ( p  
ISSN:0932-0067
1432-0711
DOI:10.1007/s00404-015-3964-y