Tumor-suppressive microRNAs (miR-26a/b, miR-29a/b/c and miR-218) concertedly suppressed metastasis-promoting LOXL2 in head and neck squamous cell carcinoma

In spite of considerable advances in multimodality therapy, including surgery, radiotherapy and chemotherapy, the overall survival rate for patients with head and neck squamous cell carcinoma (HNSCC) is very poor (only 15-45%). Understanding the molecular mechanisms of metastatic pathways underlying...

Full description

Bibliographic Details

Published in:	Journal of human genetics 2016-02, Vol.61 (2), p.109-118
Main Authors:	Fukumoto, Ichiro, Kikkawa, Naoko, Matsushita, Ryosuke, Kato, Mayuko, Kurozumi, Akira, Nishikawa, Rika, Goto, Yusuke, Koshizuka, Keiichi, Hanazawa, Toyoyuki, Enokida, Hideki, Nakagawa, Masayuki, Okamoto, Yoshitaka, Seki, Naohiko
Format:	Article
Language:	English
Subjects:	Amino Acid Oxidoreductases - genetics Amino Acid Oxidoreductases - metabolism Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell Line, Tumor Cell Movement Cell Proliferation Gene Expression Regulation, Neoplastic Head and Neck Neoplasms - genetics Head and Neck Neoplasms - metabolism Head and Neck Neoplasms - pathology Humans MicroRNAs - metabolism Squamous Cell Carcinoma of Head and Neck
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!