Dissecting the Molecular Network of Virus-Plant Interactions: The Complex Roles of Host Factors

A successful infection by a plant virus results from the complex molecular interplay between the host plant and the invading virus. Thus, dissecting the molecular network of virus-host interactions advances the understanding of the viral infection process and may assist in the development of novel a...

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Bibliographic Details
Published in:Annual review of phytopathology 2015-08, Vol.53 (1), p.45-66
Main Author: Wang, Aiming
Format: Article
Language:English
Subjects:
Crops, Agricultural - virology
Plant Diseases - virology
Plant Viruses - genetics
Plant Viruses - physiology
positive-sense RNA virus
RNA Viruses - genetics
RNA Viruses - physiology
viral genome translation
viral intercellular movement
viral protein modification
viral replication complex
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Summary:A successful infection by a plant virus results from the complex molecular interplay between the host plant and the invading virus. Thus, dissecting the molecular network of virus-host interactions advances the understanding of the viral infection process and may assist in the development of novel antiviral strategies. In the past decade, molecular identification and functional characterization of host factors in the virus life cycle, particularly single-stranded, positive-sense RNA viruses, have been a research focus in plant virology. As a result, a number of host factors have been identified. These host factors are implicated in all the major steps of the infection process. Some host factors are diverted for the viral genome translation, some are recruited to improvise the viral replicase complexes for genome multiplication, and others are components of transport complexes for cell-to-cell spread via plasmodesmata and systemic movement through the phloem. This review summarizes current knowledge about host factors and discusses future research directions.
ISSN:0066-4286
1545-2107
DOI:10.1146/annurev-phyto-080614-120001