The Role of Prophylactic Antibiotics After Minimally Invasive Pyeloplasty With Ureteral Stent Placement in Children

Objective To determine whether children discharged with prophylactic antibiotics following laparoscopic pyeloplasty with indwelling ureteral stent have a decrease risk of postoperative urinary tract infections (UTIs) compared to those discharged without antibiotics. Materials and Methods A retrospec...

Full description

Saved in:
Bibliographic Details
Published in:Urology (Ridgewood, N.J.) N.J.), 2016-03, Vol.89, p.107-112
Main Authors: Ferroni, Matthew C, Lyon, Timothy D, Rycyna, Kevin J, Dwyer, Moira E, Schneck, Francis X, Ost, Michael C, Cannon, Glenn M, Stephany, Heidi A
Format: Article
Language:English
Subjects:
Adolescent
Antibiotic Prophylaxis
Child
Child, Preschool
Female
Humans
Kidney Pelvis - surgery
Laparoscopy
Male
Minimally Invasive Surgical Procedures
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Postoperative Complications - prevention & control
Retrospective Studies
Robotic Surgical Procedures
Stents
Ureter
Urinary Tract Infections - epidemiology
Urinary Tract Infections - etiology
Urinary Tract Infections - prevention & control
Urologic Surgical Procedures - methods
Urology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To determine whether children discharged with prophylactic antibiotics following laparoscopic pyeloplasty with indwelling ureteral stent have a decrease risk of postoperative urinary tract infections (UTIs) compared to those discharged without antibiotics. Materials and Methods A retrospective review of all minimally invasive pyeloplasties performed at our institution from January 2009 to March 2015 was conducted. Patients were discharged home with or without daily prophylactic-dose antibiotics continued until 3 days after ureteral stent removal per surgeon preference. The primary outcome was incidence of culture-positive UTI. Secondary outcomes included bacteriuria at time of stent removal and adverse events associated with extended antibiotic therapy. Results Of 163 pyeloplasties (106 robotic and 57 pure laparoscopic) performed over the study period, 126 patients were discharged on prophylactic antibiotics whereas 37 patients were discharged without prophylaxis. Groups were different with respect to median age (7.1 vs 12.0 years, P  = .03) and median duration of ureteral stent (35 days vs 28 days, P  = .02). The incidence of culture-positive UTI between the time of discharge and stent removal was comparably low between groups; 2/126 (1.6%) in the prophylaxis group and 1/37 (2.7%) in the group not on prophylaxis. At time of stent removal, perioperative urine culture was positive in 2/20 (10.0 %) patients who received prophylactic antibiotics and in 1/25 (4.0%) patients who did not ( P  = .54). Conclusion The administration of extended prophylactic antibiotics showed no significant impact on the rate of UTI following minimally invasive pyeloplasty.
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2015.11.035