Can Serum Glucose Level in Early Admission Predict Outcome in Patients with Severe Head Trauma?

Background Traumatic brain injury is a major general health concern. This study aims to evaluate a possible relationship between the serum level of glucose during admission and the outcome of patients with severe traumatic brain injury. Methods In this prospective study, 80 patients with severe trau...

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Bibliographic Details
Published in:World neurosurgery 2016-03, Vol.87, p.132-135
Main Authors: Salehpour, Firooz, Bazzazi, Amir Mohammad, Aghazadeh, Javad, Abbasivash, Rahman, Forouhideh, Yalda, Mirzaei, Farhad, Naseri Alavi, Seyed Ahmad
Format: Article
Language:English
Subjects:
Adult
Aged
Biomarkers - blood
Blood Glucose - metabolism
Craniocerebral Trauma - blood
Craniocerebral Trauma - mortality
Craniocerebral Trauma - physiopathology
Death
Female
Glasgow Coma Scale
Humans
Injury Severity Score
Male
Middle Aged
Neurosurgery
Patient Admission
Patient Discharge
Predictive Value of Tests
Prognosis
Prospective Studies
Serum glucose level
Severe head trauma
Trauma
Traumatic brain injury
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Summary:Background Traumatic brain injury is a major general health concern. This study aims to evaluate a possible relationship between the serum level of glucose during admission and the outcome of patients with severe traumatic brain injury. Methods In this prospective study, 80 patients with severe traumatic brain injury were recruited from the emergency department of Urmia Imam Khomeini Hospital. Serum level of glucose was measured at the time of admission and its correlation was investigated with the Glasgow Coma Scale score (on admission, 24 hours, 48 hours, and 1 week later, and at discharge) and Glasgow Outcome Score. In addition, the value of admission serum glucose was compared between deceased and discharged patients. Results Eighty patients with severe head trauma, 71 men (88%) and 9 women (11.2%) with a mean age of 31.71 ± 15.66 years, were enrolled into the study. The in-hospital mortality rate was 25% ( n  = 20). There was no significant correlation between serum glucose level and Glasgow Coma Scale score (at different intervals) or Glasgow Outcome Score. The mean serum level of glucose was comparable between deceased and discharged patients (186.10 ± 51.36 vs. 187.98 ± 76.03 mg/dL, respectively; P  = 0.91). Conclusions Admission serum glucose is not a significant indicator of outcome in patients with severe head trauma.
ISSN:1878-8750
1878-8769
DOI:10.1016/j.wneu.2015.11.048