Catheter ablation of atrial fibrillation in patients with concomitant sinus bradycardia—Insights from the German Ablation Registry

Abstract Aims This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. Methods From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into...

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Bibliographic Details
Published in:Journal of electrocardiology 2016-03, Vol.49 (2), p.117-123
Main Authors: Zylla, Maura M., MD, Brachmann, Johannes, MD, Lewalter, Thorsten, MD, Hoffmann, Ellen, MD, Kuck, Karl-Heinz, MD, Andresen, Dietrich, MD, Willems, Stephan, MD, Hochadel, Matthias, PhD, Senges, Jochen, MD, Katus, Hugo A., MD, Thomas, Dierk, MD
Format: Article
Language:English
Subjects:
Atrial fibrillation
Atrial Fibrillation - mortality
Atrial Fibrillation - surgery
Body Surface Potential Mapping - mortality
Body Surface Potential Mapping - utilization
Bradycardia - mortality
Bradycardia - surgery
Cardiovascular
Catheter ablation
Catheter Ablation - mortality
Catheter Ablation - utilization
Comorbidity
Complications
Female
Germany - epidemiology
Humans
Male
Middle Aged
Operative Time
Postoperative Complications - mortality
Prevalence
Registries
Registry
Retrospective Studies
Risk Factors
Sinus bradycardia
Sinus node disease
Surgery, Computer-Assisted - mortality
Surgery, Computer-Assisted - utilization
Survival Rate
Treatment Outcome
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Summary:Abstract Aims This investigation addresses procedural characteristics of catheter ablation in patients with atrial fibrillation (AF) and sinus bradycardia. Methods From the prospective, multi-center German Ablation Registry 1073 patients with sinus rhythm at the time of AF ablation were divided into two groups according to heart rate at start of procedure (A, < 60 beats per minute (bpm), n = 197; B, 60–99 bpm, n = 876). Results Acute procedural success was high (≥ 98%) and similar between groups. Procedure duration and energy application time were increased in group A (180 min vs. 155 min and 2561 s vs. 1879 s, respectively). Major complications were more frequent in group A (2.2% vs. 0.5%), and a greater proportion of these patients was discharged under antiarrhythmic medication (64% vs. 52%). Conclusion Catheter ablation of AF with concomitant sinus bradycardia is associated with high procedural efficacy, longer procedure- and energy application durations, and a slightly elevated complication rate.
ISSN:0022-0736
1532-8430
DOI:10.1016/j.jelectrocard.2015.12.007