Incidental Gallbladder Cancer Visualized From Posttreatment 131I Whole-Body Scan

ABSTRACTA 72-year-old woman with papillary thyroid cancer post-total thyroidectomy was referred for post-I treatment whole-body scan. Images revealed focal uptake within the gallbladder. Cholecystectomy was subsequently performed, and the pathology report showed well-differentiated adenocarcinoma. G...

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Bibliographic Details
Published in:Clinical nuclear medicine 2016-03, Vol.41 (3), p.e162-e163
Main Authors: Anongpornjossakul, Yoch, Utamakul, Chirawat, Chamroonrat, Wichana, Kositwattanarerk, Arpakorn, Thamnirat, Kanungnij, Sritara, Chanika
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnostic imaging
Adenocarcinoma - secondary
Aged
Carcinoma - pathology
Carcinoma - radiotherapy
Carcinoma, Papillary
False Positive Reactions
Female
Gallbladder Neoplasms - diagnostic imaging
Gallbladder Neoplasms - secondary
Humans
Incidental Findings
Iodine Radioisotopes - therapeutic use
Radionuclide Imaging
Radiopharmaceuticals - therapeutic use
Thyroid Cancer, Papillary
Thyroid Neoplasms - pathology
Thyroid Neoplasms - radiotherapy
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Summary:ABSTRACTA 72-year-old woman with papillary thyroid cancer post-total thyroidectomy was referred for post-I treatment whole-body scan. Images revealed focal uptake within the gallbladder. Cholecystectomy was subsequently performed, and the pathology report showed well-differentiated adenocarcinoma. Given a history of papillary thyroid cancer, the iodine uptake was reasonably explained as metastasis; however, gallbladder metastasis was extremely infrequent. Literature described the incidental radioiodine retention in the gallbladder as false-positive findings, which can be normal variants or benign hepatobiliary conditions. Primary gallbladder malignancy could be counted for another possibility despite controversial mechanism of uptake.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000001019