High-resolution time-lapse tomography of rat vertebrae during compressive loading: deformation response analysis

This paper is focused on investigation of mechanical properties of rat vertebrae during compressive loading in the longitudinal direction of rat's spine. High-resolution time-lapse micro-tomography was used as a tool to create models of the inner structure and deformed shape in pre-defined defo...

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Bibliographic Details
Published in:Journal of instrumentation 2014-05, Vol.9 (5), p.C05054-C05054
Main Authors: Fíla, T, Kytýř, D, Zlámal, P, Kumpová, I, Doktor, T, Koudelka, P, Jiroušek, O
Format: Article
Language:English
Subjects:
Computer simulation
Deformation
Detectors
Devices
Finite element method
Mathematical analysis
Tomography
Vertebrae
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Summary:This paper is focused on investigation of mechanical properties of rat vertebrae during compressive loading in the longitudinal direction of rat's spine. High-resolution time-lapse micro-tomography was used as a tool to create models of the inner structure and deformed shape in pre-defined deformation steps. First, peripheral areas of vertebra specimen were embedded in polymethyl methacrylate to obtain proper boundary conditions of contact between specimen and loading plattens. Experimental loading device designed for application in X-ray setups was utilized to compress the vertebrae in several deformation steps. High-resolution micro-tomography scanning was carried out at each deformation step. Specimen was irradiated in tomography device equipped with microfocus X-ray tube with 5 mu m focal spot size and large area flat panel detector. Spatial resolution of reconstructed three-dimensional images was approximately 10 mu m. Digital volume correlation algorithm was utilized in order to assess displacements in the microstructure in every loading increment. Finite element model of vertebra was created from volumetric data reconstructed from tomography of the undeformed specimen. Simulated compressive test of the developed finite element model was performed in order to compare stiffness and displacements obtained by digital volume correlation and finite element simulation.
ISSN:1748-0221
1748-0221
DOI:10.1088/1748-0221/9/05/C05054