Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study

Summary Objective Radiographic disease and knee pain are thought to decrease physical activity in people with knee osteoarthritis (OA), but this has not been formally studied. We examined change in objectively measured daily walking over 2 years and evaluated the association of certain risk factors...

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Published in:	Osteoarthritis and cartilage 2016-02, Vol.24 (2), p.246-253
Main Authors:	White, D.K, Tudor-Locke, C, Zhang, Y, Niu, J, Felson, D.T, Gross, K.D, Nevitt, M.C, Lewis, C.E, Torner, J, Neogi, T
Format:	Article
Language:	eng
Subjects:	Aged Arthralgia - complications Arthralgia - physiopathology Daily walking Depression - complications Depression - physiopathology Female Humans Knee osteoarthritis Longitudinal Studies Male Middle Aged Motor Activity - physiology Osteoarthritis, Knee - complications Osteoarthritis, Knee - physiopathology Physical activity Prospective Studies Rheumatology Risk Walking
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Summary:	Summary Objective Radiographic disease and knee pain are thought to decrease physical activity in people with knee osteoarthritis (OA), but this has not been formally studied. We examined change in objectively measured daily walking over 2 years and evaluated the association of certain risk factors with reduced walking among adults with or at risk of knee OA. Design Steps/day over 7 days were collected at baseline and 2 years later in subjects with or at risk of knee OA from the Multicenter Osteoarthritis Study using a StepWatch. We evaluated the presence of radiographic knee osteoarthritis (ROA), knee pain, worsening of ROA and pain over 2 years, obesity, depressive symptoms, living situation, catastrophizing, fatigue, widespread pain and comorbidities with 2-year change in daily walking using regression models adjusted for potential confounders. Results 1318 met inclusion criteria (age 66.9 ± 7.7, 59% women, BMI 30.6 ± 5.9) and walked 126 ± 1700 steps/day fewer steps at 2 years (95% CI [−218, −35]). People with depressive symptoms at baseline walked 455 fewer steps/day [−872, −68], and there was a trend for people with ROA worsening to walk 183 fewer steps/day [−377.5, 11.7]. No other factors met statistical significance for change in daily walking. Conclusion Adults with or at risk of knee OA experienced only minimal declines in daily walking over 2 years. Nonetheless, depressive symptoms and may be worsening ROA are associated with a decline in steps/day in adults with or at risk of knee OA.
ISSN:	1063-4584 1522-9653