Prospective validation of predictive value of abdominal computed tomography scan on time to first treatment in Rai 0 chronic lymphocytic leukemia patients: results of the multicenter O-CLL1-GISL study

Objective We performed an external and multicentric validation of the predictive value of abdominal computed tomography (aCT) on time to first treatment (TTFT) in early stage chronic lymphocytic leukemia (CLL) patients. Methods aCT was performed at diagnosis in 181 Rai 0 patients enrolled in the O‐C...

Full description

Saved in:
Bibliographic Details
Published in:European journal of haematology 2016-01, Vol.96 (1), p.36-45
Main Authors: Gentile, Massimo, Cutrona, Giovanna, Molica, Stefano, Ilariucci, Fiorella, Mauro, Francesca R., Di Renzo, Nicola, Di Raimondo, Francesco, Vincelli, Iolanda, Todoerti, Katia, Matis, Serena, Musolino, Caterina, Fabris, Sonia, Lionetti, Marta, Levato, Luciano, Zupo, Simona, Angrilli, Francesco, Consoli, Ugo, Festini, Gianluca, Longo, Giuseppe, Cortelezzi, Agostino, Musto, Pellegrino, Federico, Massimo, Neri, Antonino, Ferrarini, Manlio, Morabito, Fortunato
Format: Article
Language:English
Subjects:
Abdomen
abdominal CT scan
ADP-ribosyl Cyclase 1 - blood
beta 2-Microglobulin - blood
chronic lymphocytic leukemia
clinical monoclonal B-cell lymphocytosis
early stage
Female
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - blood
Leukemia, Lymphocytic, Chronic, B-Cell - diagnostic imaging
Leukemia, Lymphocytic, Chronic, B-Cell - therapy
Male
Middle Aged
prognosis
Radiography, Abdominal
Tomography, X-Ray Computed
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective We performed an external and multicentric validation of the predictive value of abdominal computed tomography (aCT) on time to first treatment (TTFT) in early stage chronic lymphocytic leukemia (CLL) patients. Methods aCT was performed at diagnosis in 181 Rai 0 patients enrolled in the O‐CLL1‐GISL trial (clinicaltrial.gov ID:NCT00917549). Results Fifty‐five patients showed an abnormal aCT. Patients with an abnormal aCT showed a significantly shorter TTFT than those with normal aCT (P 
ISSN:0902-4441
1600-0609
DOI:10.1111/ejh.12545