Mesenchymal stem cells and infectious diseases: Smarter than drugs

Highlights • MSCs (BMSCs) can suppress T cell proliferation. • MSCs interact with a variety of pathogens. • MSCs affect cells of the immune system and are affected by them. • MSCs have a promise for new cellular therapy in humans.

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Bibliographic Details
Published in:Immunology letters 2015-12, Vol.168 (2), p.208-214
Main Authors: Mezey, Éva, Nemeth, Krisztián
Format: Article
Language:English
Subjects:
Adaptive Immunity - immunology
Allergy and Immunology
Animals
BMSC
Bone Marrow Cells - cytology
Bone Marrow Cells - immunology
Bone Marrow Cells - metabolism
Communicable Diseases - immunology
Communicable Diseases - microbiology
Communicable Diseases - parasitology
Cytokines - immunology
Cytokines - metabolism
Humans
Immune-regulatory effects of MSC
Immunity, Innate - immunology
Mesenchymal Stem Cell Transplantation - methods
Mesenchymal Stromal Cells - cytology
Mesenchymal Stromal Cells - immunology
Mesenchymal Stromal Cells - metabolism
MSC
MSC and pathogen interactions
Toll-Like Receptors - immunology
Toll-Like Receptors - metabolism
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Description
Summary:Highlights • MSCs (BMSCs) can suppress T cell proliferation. • MSCs interact with a variety of pathogens. • MSCs affect cells of the immune system and are affected by them. • MSCs have a promise for new cellular therapy in humans.
ISSN:0165-2478
1879-0542
DOI:10.1016/j.imlet.2015.05.020