Pregnancy and Thoracic Aortic Disease: Managing the Risks

Abstract The most common aortopathies in women of childbearing age are bicuspid aortic valve, coarctation of the aorta, Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, SMAD3 aortopathy, Turner syndrome, and familial thoracic aneurysm and dissection. The hemodynamic and hormonal change...

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Bibliographic Details
Published in:Canadian journal of cardiology 2016, Vol.32 (1), p.78-85
Main Authors: Wanga, Shaynah, MD, Silversides, Candice, MD, Dore, Annie, MD, de Waard, Vivian, PhD, Mulder, Barbara, MD, PhD
Format: Article
Language:English
Subjects:
Aorta, Thoracic
Aortic Diseases - diagnosis
Aortic Diseases - therapy
Cardiovascular
Disease Management
Female
Humans
Pregnancy
Pregnancy Complications, Cardiovascular
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Summary:Abstract The most common aortopathies in women of childbearing age are bicuspid aortic valve, coarctation of the aorta, Marfan syndrome, Ehlers-Danlos syndrome, Loeys-Dietz syndrome, SMAD3 aortopathy, Turner syndrome, and familial thoracic aneurysm and dissection. The hemodynamic and hormonal changes of pregnancy increase the risk of progressive dilatation or dissection of the aorta in these women. The presence of hypertension increases the risk further. Therefore, appropriate preconception counselling is advised. For women who become pregnant, serial follow-up by a specialized multidisciplinary team throughout pregnancy and postpartum period is required. In this review we discuss risk assessment and management strategies for women with aortopathies.
ISSN:0828-282X
1916-7075
DOI:10.1016/j.cjca.2015.09.003