Measles Virus Infection in Pediatric Liver Transplantation Recipients

Abstract Objective This study was conducted to analyze the clinical characteristics and outcome of measles in pediatric liver transplant recipients. Methods This study includes a retrospective data analysis of five pediatric liver transplant recipients with measles who were treated at the Liver Tran...

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Bibliographic Details
Published in:	Transplantation proceedings 2015-11, Vol.47 (9), p.2715-2718
Main Authors:	Liu, Y, Sun, L.-Y, Zhu, Z.-J, Lin, W, Qu, W, Zeng, Z.-G
Format:	Article
Language:	eng
Subjects:	Beijing Child, Preschool Female Humans Immunocompromised Host Infant Liver Transplantation - adverse effects Liver Transplantation - methods Male Measles - complications Measles virus Pneumonia, Viral - etiology Postoperative Complications - virology Respiration, Artificial Respiratory Insufficiency - therapy Respiratory Insufficiency - virology Retrospective Studies Surgery
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Summary:	Abstract Objective This study was conducted to analyze the clinical characteristics and outcome of measles in pediatric liver transplant recipients. Methods This study includes a retrospective data analysis of five pediatric liver transplant recipients with measles who were treated at the Liver Transplant Section, Beijing Friendship Hospital, China, from March to April 2014. Results The clinical manifestations of measles in pediatric liver transplant recipients were serious. There were three cases complicated with pneumonia, and one with laryngitis. Two cases presented with severe measles pneumonia that developed into severe respiratory failure requiring mechanical ventilation. Four patients recovered after treatment and one patient died of respiratory failure. Conclusion Pediatric liver transplant recipients with measles are at high risk of severe pneumonia. Measles pneumonitis is frequently fatal to immunocompromised pediatric patients. Treatment should be initiated as soon as possible.
ISSN:	0041-1345 1873-2623