Liver Transplantation Outcomes Using Grafts From Donors Older Than the Age of 80 Years

Abstract We performed a retrospective cohort study between 2002 and 2014 to compare liver transplantation outcomes between recipients of grafts from donors older than and younger than the age of 80 years. Numerical variables were compared with the Student t test when their distribution was normal an...

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Bibliographic Details
Published in:Transplantation proceedings 2015-11, Vol.47 (9), p.2645-2646
Main Authors: Rabelo, A.V, Alvarez, M.J, Méndez, C.S.M, Villegas, M.T, MGraneroa, K, Becerra, A, Dominguez, M, Raya, A.M, Exposito, M, Suárez, Y.F
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Chi-Square Distribution
Child
Female
Graft Rejection
Graft Survival
Humans
Length of Stay
Liver - surgery
Liver Transplantation - mortality
Male
Middle Aged
Reoperation - statistics & numerical data
Retrospective Studies
Severity of Illness Index
Surgery
Tissue Donors - statistics & numerical data
Transplants
Treatment Outcome
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Summary:Abstract We performed a retrospective cohort study between 2002 and 2014 to compare liver transplantation outcomes between recipients of grafts from donors older than and younger than the age of 80 years. Numerical variables were compared with the Student t test when their distribution was normal and the Mann-Whitney test when it was not, whereas categorical variables were compared with Pearson chi-squared test or Fisher test, as appropriate; P  < .05 was considered significant. The study included 312 patients with organs from donors younger than 80 years of age and 17 with organs from older donors. The 2 recipient groups did not significantly differ in weight, height, gender, body mass index (BMI), CHILD or MELD score, intensive care unit (ICU) or hospital stay, need for intraoperative hemoderivatives, postreperfusion syndrome, biliary or vascular complications, ischemic cholangiopathy, number of repeat surgeries, graft rejection, retransplantation, or survival at 6 months. Although earlier studies considered livers from elderly donors to be suboptimal, our results support the proposition that octogenarian donors can be an excellent source of liver grafts.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2015.10.004