Phenotyping juvenile myoclonic epilepsy. Praxis induction as a biomarker of unfavorable prognosis

Highlights • There is a male preponderance in juvenile myoclonic epilepsy patients with praxis induction. • Praxis induction is related to focal epileptiform discharges. • Praxis induction is related to loss of the characteristic chronodependency of juvenile myoclonic epilepsy and with reduced respo...

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Bibliographic Details
Published in:Seizure (London, England) England), 2015-11, Vol.32, p.62-68
Main Authors: Uchida, Carina Gonçalves Pedroso, de Carvalho, Kelly Cristina, Guaranha, Mirian Salvadori Bittar, Guilhoto, Laura Maria Figueiredo F, de Araújo Filho, Gerardo Maria, Wolf, Peter, Yacubian, Elza Márcia Targas
Format: Article
Language:English
Subjects:
Adult
Anticonvulsants - therapeutic use
Brain - drug effects
Brain - physiopathology
Child
Chronosensitivity
Circadian Rhythm - physiology
Comorbidity
Electroencephalography - methods
Endophenotypes
Female
Follow-Up Studies
Humans
Juvenile myoclonic epilepsy
Male
Mental Disorders - epidemiology
Myoclonic Epilepsy, Juvenile - diagnosis
Myoclonic Epilepsy, Juvenile - drug therapy
Myoclonic Epilepsy, Juvenile - epidemiology
Myoclonic Epilepsy, Juvenile - physiopathology
Neurology
Praxis induction
Prevalence
Prognosis
Quality of Life
Video Recording - methods
Young Adult
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Summary:Highlights • There is a male preponderance in juvenile myoclonic epilepsy patients with praxis induction. • Praxis induction is related to focal epileptiform discharges. • Praxis induction is related to loss of the characteristic chronodependency of juvenile myoclonic epilepsy and with reduced response to antiepileptic drugs.
ISSN:1059-1311
1532-2688
DOI:10.1016/j.seizure.2015.09.011