The relevance of neuropsychiatric symptoms and cognitive problems in new-onset epilepsy — Current knowledge and understanding

Abstract Neurobehavioral and cognition problems are highly prevalent in epilepsy, but most research studies to date have not adequately addressed the precise nature of the relationship between these comorbidities and seizures. To address this complex issue and to facilitate collaborative, innovative...

Full description

Saved in:
Bibliographic Details
Published in:Epilepsy & behavior 2015-10, Vol.51, p.199-209
Main Authors: Pohlmann-Eden, B, Aldenkamp, A, Baker, G.A, Brandt, C, Cendes, F, Coras, R, Crocker, C.E, Helmstaedter, C, Jones-Gotman, M, Kanner, A.M, Mazarati, A, Mula, M, Smith, M.L, Omisade, A, Tellez-Zenteno, J, Hermann, B.P
Format: Article
Language:English
Subjects:
Animals
Canada - epidemiology
Cognition
Cognition Disorders - diagnosis
Cognition Disorders - epidemiology
Cognition Disorders - psychology
Comorbidity
Comprehension
Congresses as Topic
Epilepsy - diagnosis
Epilepsy - epidemiology
Epilepsy - psychology
Etiology
First seizure
Humans
Mental Disorders - diagnosis
Mental Disorders - epidemiology
Mental Disorders - psychology
Neurology
New study designs
New-onset epilepsy
Nova Scotia - epidemiology
Psychiatric comorbidities
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Neurobehavioral and cognition problems are highly prevalent in epilepsy, but most research studies to date have not adequately addressed the precise nature of the relationship between these comorbidities and seizures. To address this complex issue and to facilitate collaborative, innovative research in the rising field of neurobehavioral comorbidities and cognition disturbances in new-onset epilepsy, international epilepsy experts met at the 3rd Halifax International Epilepsy Conference & Retreat at White Point, South Shore, Nova Scotia, Canada from September 18 to 20, 2014. This Conference Proceedings provides a summary of the conference proceedings. Specifically, the following topics are discussed: (i) role of comorbidities in epilepsy diagnosis and management, (ii) role of antiepileptic medications in understanding the relationship between epilepsy and neurobehavioral and cognition problems, and (iii) animal data and diagnostic approaches. Evidence to date, though limited, strongly suggests a bidirectional relationship between epilepsy and cognitive and psychiatric comorbidities. In fact, it is likely that seizures and neurobehavioral problems represent different symptoms of a common etiology or network-wide disturbance. As a reflection of this shared network, psychiatric comorbidities and/or cognition problems may actually precede the seizure occurrence and likely get often missed if not screened.
ISSN:1525-5050
1525-5069
DOI:10.1016/j.yebeh.2015.07.005