Severity of pneumococcal versus non-pneumococcal acute otitis media in children

Background Pneumococcal acute otitis media (AOM) has been previously considered as a more severe disease than that caused by other otopathogens, based on clinical and/or otologic scores. We sought to test this hypothesis in the pneumococcal conjugated vaccine (PCV) era. Methods Children 15 000/μL, a...

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Bibliographic Details
Published in:Clinical otolaryngology 2015-08, Vol.40 (4), p.370-377
Main Authors: Ovnat Tamir, S., Roth, Y., Goldfarb, A., Grotto, I., Marom, T.
Format: Article
Language:English
Subjects:
Acute Disease
Child
Child, Preschool
Female
Humans
Infant
Male
Otitis Media - microbiology
Otitis Media - prevention & control
Pneumococcal Vaccines
Retrospective Studies
Severity of Illness Index
Streptococcal Infections - microbiology
Streptococcal Infections - prevention & control
Streptococcus pneumoniae
Streptococcus pneumoniae - isolation & purification
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Summary:Background Pneumococcal acute otitis media (AOM) has been previously considered as a more severe disease than that caused by other otopathogens, based on clinical and/or otologic scores. We sought to test this hypothesis in the pneumococcal conjugated vaccine (PCV) era. Methods Children 15 000/μL, and elevated C‐reactive protein (CRP) level was considered as >50 mg/L. Results Of 295 eligible AOM episodes, 106 (36%) were culture positive. Children in the pneumococcal group (65, 61%) had a significantly higher WBC counts and higher CRP levels, were more often
ISSN:1749-4478
1749-4486
DOI:10.1111/coa.12384