Analysis of Renal Functional Outcomes After Radical or Partial Nephrectomy for Renal Masses ≥7 cm Using the RENAL Score

Objective To determine if partial nephrectomy (PN) confers a renal functional benefit compared to radical nephrectomy (RN) for clinical T2 renal masses (T2RM) when adjusting for tumor complexity characterized by the RENAL nephrometry score. Methods A 2-center study of 202 patients with T2RM undergoi...

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Published in:Urology (Ridgewood, N.J.) N.J.), 2015-08, Vol.86 (2), p.312-320
Main Authors: Kopp, Ryan P, Liss, Michael A, Mehrazin, Reza, Wang, Song, Lee, Hak J, Jabaji, Ramzi, Mirheydar, Hossein S, Gillis, Kyle, Patel, Nishant, Palazzi, Kerrin L, Wan, Jim Y, Patterson, Anthony L, Derweesh, Ithaar H
Format: Article
Language:English
Subjects:
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - surgery
Female
Humans
Kidney - physiology
Kidney Function Tests
Kidney Neoplasms - pathology
Kidney Neoplasms - surgery
Male
Middle Aged
Nephrectomy - methods
Recovery of Function
Retrospective Studies
Tumor Burden
Urology
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Summary:Objective To determine if partial nephrectomy (PN) confers a renal functional benefit compared to radical nephrectomy (RN) for clinical T2 renal masses (T2RM) when adjusting for tumor complexity characterized by the RENAL nephrometry score. Methods A 2-center study of 202 patients with T2RM undergoing RN (122) or PN (80) (median follow-up, 41.5 months). RN and PN cohorts were subanalyzed according to RENAL sum as a categorical variable of 
ISSN:0090-4295
1527-9995
DOI:10.1016/j.urology.2015.02.067