Necrotizing tracheobronchial aspergillosis in an immunosuppressed patient. Report of one case

Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficie...

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Bibliographic Details
Published in:Revista medíca de Chile 2015-04, Vol.143 (4), p.525-530
Main Authors: Andresen, Max H, Venegas, Carmen Paz, Vega, Claudia, Aravena, Carlos, Andresen, Max V
Format: Article
Language:Spanish
Subjects:
Adult
Antifungal Agents - therapeutic use
Aspergillosis - complications
Aspergillus
Bronchitis - microbiology
Bronchoscopy
Fatal Outcome
Female
Fingers - pathology
Humans
Immunocompromised Host
Lupus Erythematosus, Systemic - complications
Necrosis
Shock, Septic - complications
Toes - pathology
Tracheitis - microbiology
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Summary:Necrotizing tracheobronchitis due to Aspergillus spp is a rare form of invasive aspergillosis. This infection is limited to or predominant in the bronchial tree. The clinical evolution is gradual: from mild non-specific manifestations of acute tracheobronchitis to severe acute respiratory insufficiency determined by a bronchial obstruction syndrome. We report a 38 years old female with systemic lupus erythematosus treated with methylprednisolone and cyclophosphamide. She developed an invasive aspergillosis, severe respiratory failure with predominant tracheobronchial damage and upper respiratory complications.
ISSN:0034-9887
0717-6163
DOI:10.4067/S0034-98872015000400016