Widespread contamination of coastal sediments in the Transmanche Channel with anti-androgenic compounds

•Anti-androgen (AA) activity was detected in extracts of coastal sediments.•AA activity was 0.2–224.3±38.4μg flutamide equivalents/g dry weight of sediment.•AA activity was present in clams due to uptake of a series of 4 or 5 ring PAHs. This study analysed the levels of androgen receptor antagonist...

Full description

Saved in:
Bibliographic Details
Published in:Marine pollution bulletin 2015-06, Vol.95 (2), p.590-597
Main Authors: Alvarez-Muñoz, Diana, Indiveri, Paolo, Rostkowski, Pawel, Horwood, Julia, Greer, Emily, Minier, Christophe, Pope, Nick, Langston, William J., Hill, Elizabeth M.
Format: Article
Language:eng
Subjects:
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•Anti-androgen (AA) activity was detected in extracts of coastal sediments.•AA activity was 0.2–224.3±38.4μg flutamide equivalents/g dry weight of sediment.•AA activity was present in clams due to uptake of a series of 4 or 5 ring PAHs. This study analysed the levels of androgen receptor antagonist activity in extracts of coastal sediments sampled from estuaries in southern UK and northern France. Anti-androgenic (AA) activity varied between
ISSN:0025-326X
1879-3363