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Omaezallene from Red Alga Laurencia sp.: Structure Elucidation, Total Synthesis, and Antifouling Activity
Natural antifouling products have been the subject of considerable attention. We screened marine algae for antifouling activity and discovered omaezallenes, the new bromoallene‐containing natural products isolated from the red alga Laurencia sp. Described is the isolation, structure elucidation, and...
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Published in: | Angewandte Chemie 2014-04, Vol.126 (15), p.3990-3993 |
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Main Authors: | , , , , , , , , , , , , , |
Format: | Article |
Language: | eng ; ger |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Natural antifouling products have been the subject of considerable attention. We screened marine algae for antifouling activity and discovered omaezallenes, the new bromoallene‐containing natural products isolated from the red alga Laurencia sp. Described is the isolation, structure elucidation, and total syntheses of omaezallenes. The relative and absolute configurations of natural omaezallenes were unambiguously established through total synthesis. The antifouling activities and ecotoxicity of omaezallenes were also evaluated.
Ein neuer bromierter Naturstoff – das aus der Rotalge Laurencia sp. isolierte Omaezallen – wurde synthetisiert und einer NMR‐Strukturaufklärung unterzogen. Die Wirkung von Omaezallen und seinen Isomeren gegen Bewuchs durch Cyprislarven der Gestreiften Seepocke (Amphibalanus amphitrite) wurde untersucht. |
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ISSN: | 0044-8249 1521-3757 |
DOI: | 10.1002/ange.201311175 |