Synthesis and Antimicrobial Activity of New Ureas from (1S,2S)-2-Amino-1-(4-Nitrophenyl)-1,3-Propanediol

A series of new urea derivatives were synthesized from (1 S ,2 S )-2-amino-1-(4-nitrophenyl)-1,3-propanediol and their antimicrobial activities were studied. Of the eight ureas synthesized here, only one compound had weak antimicrobial activity in relation to B. cereus and Candida spp.

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Bibliographic Details
Published in:Pharmaceutical chemistry journal 2015-04, Vol.49 (1), p.10-12
Main Authors: Madesclaire, M., Coudert, P., Lyamin, A. V., Sharipova, S. Kh, Zaitseva, Yu. V., Zaitsev, V. P.
Format: Article
Language:English
Subjects:
Candida
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
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Summary:A series of new urea derivatives were synthesized from (1 S ,2 S )-2-amino-1-(4-nitrophenyl)-1,3-propanediol and their antimicrobial activities were studied. Of the eight ureas synthesized here, only one compound had weak antimicrobial activity in relation to B. cereus and Candida spp.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-015-1213-0